ATPCL;chm

Lifespan changes: From wild type to ATPCL;chm DF = decrease in function; IF = increase in function

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Genetic mutants with ATPCL, chm alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Strain

    P{PZ}ATPCL[01446];chm[14]

  • Temperature °C

    25

  • Diet

    water, 1.2% agar, 1.8% yeast, 1% soja, 2.2% sugar syrup, 8% corn extract, 8% malt extract, 0.24% Nipagin, and 6.25 ul/l of propionic acid and yeast extra powder

  • Lifespan (days)

    54.0

  • Lifespan comparisons

    Double mutant ATPCL(DF);chm(DF) has a lifespan of 54.0 days, while single mutant ATPCL(DF) has a lifespan of 57.0 days.

  • Citation
    View abstract

    Peleg S et al., 2016, Life span extension by targeting a link between metabolism and histone acetylation in Drosophila. EMBO Rep. 17(3):455-69 PubMed 26781291 Click here to select all mutants from this PubMed ID in the graph

Search genes: ATPCL chm
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

ATP citrate lyase


Locus: Dmel_CG8322


  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

chameau


Locus: Dmel_CG5229


Orthologs of ATPCL;chm in SynergyAge
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Species Gene
Orthologs of ATPCL in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of chm in SynergyAge
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Species Gene
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Contact
Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania
Email:

Group webpage: www.aging-research.group