Download SynergyAge database
Release date: April 2020
Number of gene combinations: 1833
The SQL tables and the JSON file have the following information and structure:
Table (models): each row represents a cohort for a mutant (or for wild type)
Table (model_interactions): each row represents a SynergyAge transition from an n-mutant to the corresponding (n+1)-mutant
In the CSV file, each row represents a comparison between wild type (where available), n-mutant, 1-mutant (where available) and (n+1)-mutant, with all the gene-centric information included within the row.
SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.
If you would like to cite this database please use:
Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z
Group webpage: www.aging-research.group